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Year : 2015  |  Volume : 8  |  Issue : 1  |  Page : 145-147

Prevalence of antithyroid antibodies in chronic urticaria

Dermatology Department, Aster Gardens Medical Centre, Dubai, United Arab Emirates

Correspondence Address:
Santosh Daflapurkar
Specialist Dermatologist, Dermatology Department, Aster Gardens Medical Centre, Dubai
United Arab Emirates
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Source of Support: None, Conflict of Interest: None

DOI: 10.7707/hmj.385

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Urticaria persisting beyond 6 weeks is classified as chronic urticaria. It is further divided into two categories: autoimmune and idiopathic. Chronic autoimmune urticaria accounts for 45% of cases, and chronic idiopathic urticaria is seen in the other 55% of cases. Sixty patients with chronic urticaria, consulted over a 2-year period, were evaluated. Complete blood count, a thyroid function test and an antithyroid antibody evaluation were advised. Patients positive for antithyroid antibodies were given immunosuppressive therapy (methotrexate) as well as antihistamines. After 6 months of treatment with methotrexate, repeat titres of antithyroid antibodies were carried out. There was a significant decline in antithyroid antibody levels. Clinically these patients could discontinue antihistamines. Five patients showed recurrence of symptoms 3 months after discontinuation of treatment, but the symptoms were mild and easily controlled with antihistamines.

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