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  Indian J Med Microbiol
 

Figure 1: Mechanism of interference from endogenous antibodies in a competitive immunoassay. (a) Competitive immunoassay without any interference resulting in a true positive or true negative result. (b) Cross-linking of capture and labelled analyte analogue in the presence of endogenous antibody, resulting in false-positive or false-negative result

Figure 1: Mechanism of interference from endogenous antibodies in a competitive immunoassay. (a) Competitive immunoassay without any interference resulting in a true positive or true negative result. (b) Cross-linking of capture and labelled analyte analogue in the presence of endogenous antibody, resulting in false-positive or false-negative result