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Hepatosplenomegaly in Rosai–Dorfman disease: A rare finding in a rare disease

 Department of Medicine, Medical D Unit, Khyber Teaching Hospital, Peshawar, Pakistan

Correspondence Address:
Farishta Waheed,
Medical D Unit, Khyber Teaching Hospital, Peshawar
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2227-2437.246134

Rosai–Dorfman disease (RDD) is a rare, usually self-limiting disease caused by a histiocytic proliferation of unknown aetiology in the lymph nodes sinuses and extranodal tissue. The condition usually presents with massive lymphadenopathy involving multiple lymph node groups in the body but is not always confined to the lymph nodes – it can also involve extranodal tissues such as the skin, liver, spleen and central nervous system. We present the case of a 50-year-old female with RDD with hepatosplenomegaly initially misdiagnosed with tuberculosis.

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