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Polyglandular autoimmune syndrome diagnosed previously as an isolated primary adrenal insufficiency

1 Department of Medicine, College of Medicine and Health Sciences (HUCOM), Hadramout University, Mukalla, Hadramout, Republic of Yemen
2 Department of Medicine, Ibnseena Teaching Hospital, Mukalla, Hadramout, Republic of Yemen

Correspondence Address:
Rasheed Mohammed Bamekhlah,
P O Box No. 8892, Mukalla, Hadramout
Republic of Yemen
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2227-2437.246133

A 32-year-old female patient diagnosed 3 years back as Addison's disease; she presented with vaginal candidiasis, oral thrush, fatigue and constipation, and the condition started since childhood and pre-puberty in succession. On examination, there were vitiligo and nail dystrophy. The investigations required done, which revealed hypoglycaemia, hypocalcaemia and hyperkalaemia; hormonal study gave a picture of primary adrenal and parathyroid insufficiency with euthyroidism. The patients finally proved to have mucosal candidiasis, primary hypoparathyroidism and Addison's disease with no thyroid abnormality. The case was diagnosed with autoimmune polyglandular syndrome (Type I).

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