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CASE REPORT
Year : 2019  |  Volume : 12  |  Issue : 2  |  Page : 83-85

Haemophagocytic lymphohistiocytosis and the challenge of early diagnosis


1 Department of Internal Medicine, Hatta Hospital, Dubai, UAE
2 Department of Haematology, Dubai Hospital, Dubai, UAE
3 Department of Intensive Care, Hatta Hospital, Dubai, UAE

Correspondence Address:
Hoda Mohamed Hammoda
Department of Internal Medicine, Hatta Hospital, Dubai
UAE
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/HMJ.HMJ_40_18

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Haemophagocytic lymphohistiocytosis (HLH) is an uncommon, life-threatening hyperinflammatory syndrome in which abnormal, ineffective energising of the immune system causes excessive activation of lymphocytes and macrophages, which can lead to hypercytokinaemia and massive tissue destruction. A high index of suspicion is necessary for early diagnosis. We report a case of HLH in a 66-year-old woman who presented with fever, pancytopenia and hepatosplenomegaly.


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