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EDUCATIONAL REVIEW
Year : 2017  |  Volume : 10  |  Issue : 2  |  Page : 143-144

The gut–brain axis – a new key to understand mind–body connection


1 Department of Emergency Medicine, Moulana Hospital, Perinthalmanna, Kerala, India
2 Department of Community Medicine, Yenapoya Medical College, Yenapoya University, Mangalore, Karnataka, India
3 Department of Surgery, Kunhitharuvayi Memorial Charitable Trust, Kerala University of Health Science, Calicut, Kerala, India

Correspondence Address:
Fahim Basheer
Department of Emergency Medicine, Moulana Hospital, Perinthalmanna, Kerala
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.7707/hmj.685

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The gut has been considered a digestive organ until the recent discovery of the gut–brain axis. The gut–brain axis is a connection through which the gut microbes are able to influence and control the emotions as well as the cognition of an individual through neuroimmunoendocrinological pathways. This article puts forth some of the well-established discoveries of the gut–brain axis, explaining the mechanism of action on how gut microbes modulate the formation of the enteric nervous system and the production of neurohormones and chemokines to alter the cognitive performance of the brain and the emotional balance of an individual through neural, immune and endocrine pathways. Moreover, this bidirectional axis acts as a new key to understand the mind–body connection in the future.


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